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Review
. 2003 Nov;134(2):169-77.
doi: 10.1046/j.1365-2249.2003.02259.x.

Relative paradigms between autoantibodies in lupus and autoantibodies in cancer

E M Tan  1 , F-D Shi
Affiliations
Review

Relative paradigms between autoantibodies in lupus and autoantibodies in cancer

E M Tan et al. Clin Exp Immunol. 2003 Nov.
No abstract available

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Figures

Fig. 1
Fig. 1
PCNA localization on nonsynchronized HEp-2 cells using human lupus autoantibody. Nuclei of cells in different phases of the cell cycle showed different patterns of staining, some with nucleolar staining associated with speckled staining at the nuclear periphery while others showed uniform fine-speckled nucleoplasmic staining. Nucleolar localization of PCNA was associated with early S phase of DNA synthesis while uniform nucleoplasmic localization was associated with mid and late S phase.
Fig. 2
Fig. 2
Immunofluorescent localization of PCNA in the protozoan Euplotes eurystomus. Cells were permeabilized before fixation and arranged with the anterior end pointing up. (a) and (b) are immunofluorescent and phase contrast images of the same field showing micronuclei (thin arrows) and the RBs of macronuclei (thick arrows). The macronuclei are in the form of inverted Cs and the cell on the right shows RB at both ends of the macronucleus at the beginning of the S phase. Frames (c–i) show immunofluorescent images of RBs advancing towards each other until fusion at the termination of S phase (from [20]).
See this image and copyright information in PMC

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