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Comparative Study
. 2003;4(3):E46.
doi: 10.1208/pt040346.

Studies on neomycin production using immobilized cells of S marinensis NUV-5 in various reactor configurations: a technical note

Poluri Ellaiah  1 , Bandi Srinivasulu, Kunamneni Adinarayana
Affiliations
Comparative Study

Studies on neomycin production using immobilized cells of S marinensis NUV-5 in various reactor configurations: a technical note

Poluri Ellaiah et al. AAPS PharmSciTech. 2003.

Abstract

Stirred tank, fluidized bed, and airlift reactors produced similar neomycin activity with immobilized cells. Packed bed reactor clearly under performed, probably because of insufficient aeration or mixing. Neomycin production using immobilized cells in fermentors requires good mixing and aeration.

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