[Modalities and limits of conservative treatment of adenocarcinoma in situ of the uterine cervix: analysis of nine cases and review of the literature]
- PMID: 14623554
- DOI: 10.1016/j.gyobfe.2003.08.016
[Modalities and limits of conservative treatment of adenocarcinoma in situ of the uterine cervix: analysis of nine cases and review of the literature]
Abstract
Objective: The aim of this study is to assess the results of conservative management of adenocarcinoma in situ (AIS) of the uterine cervix in young patients.
Patients and methods: Data of 16 patients treated for AIS were reviewed: 10 were treated initially conservatively (cold knife conization in five patients, loop excision in three patients and cervical amputation in two patients) and six radically. One patient treated initially conservatively with loop excision and positive margins underwent a completion surgery (hysterectomy).
Results: None patient had recurrence whatever the type of surgery (radical or conservative) with a mean follow-up of 74 months. Two pregnancies were observed.
Discussion and conclusions: Conservative surgery for patients with AIS could be considered in young patients. But [for] reviewing literature several conditions should be respected: careful follow-up after conservative treatment; cold knife conization; length of cone specimen >25 mm and free margins. If those criteria are respected the risk of recurrent disease under the form of invasive carcinoma is low.
Comment in
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[Methods and limits of conservative treatment for cervical adenocarcinoma: analysis of 9 cases and review of the literature].Gynecol Obstet Fertil. 2004 Jul-Aug;32(7-8):684-5. doi: 10.1016/j.gyobfe.2004.06.010. Gynecol Obstet Fertil. 2004. PMID: 15450271 French. No abstract available.
