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. 2003 Dec;74(7-8):732-5.
doi: 10.1016/j.fitote.2003.08.007.

Cytotoxic activity of Ozoroa insignis from Zimbabwe

Angela I Rea  1 , Jennifer M Schmidt, William N Setzer, Samson Sibanda, Catherine Taylor, Ephraim T Gwebu
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Cytotoxic activity of Ozoroa insignis from Zimbabwe

Angela I Rea et al. Fitoterapia. 2003 Dec.

Abstract

The crude methanol bark extract of the Zimbabwean medicinal plant, Ozoroa insignis, showed in-vitro cytotoxic activity against Hep-G2 (human hepatocellular carcinoma), MDA-MB-231 (human mammary adenocarcinoma), and 5637 (human primary bladder carcinoma). Bioactivity-directed chromatographic separation led to isolation of anacardic acid and ginkgoic acid as the cytotoxic components.

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