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Review
. 2003 Nov 22;327(7425):1222-5.
doi: 10.1136/bmj.327.7425.1222.

Joining the DoTS: new approach to classifying adverse drug reactions

J K Aronson  1 , R E Ferner
Affiliations
Review

Joining the DoTS: new approach to classifying adverse drug reactions

J K Aronson et al. BMJ. .

Abstract

A new classification system for adverse drug reactions based on time course and susceptibility as well as dose responsiveness should improve drug development and management of adverse reactions

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Figures

Figure 1
Figure 1
Credit: LIANNE PAYNE
Figure 2
Figure 2
Graphs showing how probability of adverse drug reaction (y axis) might vary with variations in time after administration (x axis, arbitrary units) and dose (z axis, arbitrary units) in people with high, medium, and low susceptibility having an adverse effect of intermediate type
See this image and copyright information in PMC

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