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Review
. 2003 Nov 24;22(53):8543-67.
doi: 10.1038/sj.onc.1207107.

A decade of caspases

Alexei Degterev  1 , Michael Boyce, Junying Yuan
Affiliations
Review

A decade of caspases

Alexei Degterev et al. Oncogene. .

Abstract

Caspases are a family of cysteine proteases that play important roles in regulating apoptosis. A decade of research has generated a wealth of information on the signal transduction pathways mediated by caspases, the distinct functions of individual caspases and the mechanisms by which caspases mediate apoptosis and a variety of physiological and pathological processes.

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