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Comment
. 2003 Oct 31;115(3):247-8.
doi: 10.1016/s0092-8674(03)00853-5.

Embryonic stem cell self-renewal, analyzed

Sally Temple  1
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Embryonic stem cell self-renewal, analyzed

Sally Temple. Cell. .
Free article

Abstract

Maintaining the pluripotency of mouse ES cells requires both LIF (leukemia inhibitory factor) and unknown factors in serum. The paper from Ying et al. in this issue of Cell shows that BMP (bone morphogenetic protein) can replace serum in this capacity, defining molecular requirements for ES cell self-renewal.

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