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Comparative Study
. 2003 Dec;47(12):3973-5.
doi: 10.1128/AAC.47.12.3973-3975.2003.

Comparative in vitro susceptibilities and bactericidal activities of investigational fluoroquinolone ABT-492 and other antimicrobial agents against human mycoplasmas and ureaplasmas

Affiliations
Comparative Study

Comparative in vitro susceptibilities and bactericidal activities of investigational fluoroquinolone ABT-492 and other antimicrobial agents against human mycoplasmas and ureaplasmas

Ken B Waites et al. Antimicrob Agents Chemother. 2003 Dec.

Abstract

We determined in vitro susceptibilities for ABT-492 and other antimicrobials against Mycoplasma pneumoniae, Mycoplasma fermentans, Mycoplasma hominis, and Ureaplasma species. ABT-492 MICs were < or =1 microg/ml, and the agent was bactericidal against selected isolates of M. pneumoniae and M. hominis. ABT-492 has potential for treatment of infections due to these microorganisms.

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References

    1. Bébéar, C. M., H. Renaudin, A. Boudjadja, and C. Bébéar. 1998. In vitro activity of BAY 12-8039, a new fluoroquinolone, against mycoplasmas. Antimicrob. Agents Chemother. 42:703-704. - PMC - PubMed
    1. Bebear, C. M., H. Renaudin, A. Bryskier, and C. Bebear. 2000. Comparative activities of telithromycin (HMR 3647), levofloxacin, and other antimicrobial agents against human mycoplasmas. Antimicrob. Agents Chemother. 44:1980-1982. - PMC - PubMed
    1. Goldstein, E. J. C., D. M. Citron, C. V. Merriam, Y. A. Warren, K. L. Tyrrell, and H. T. Fernandez. 2003. In vitro activities of ABT-492, a new fluoroquinolone, against 155 aerobic and 171 anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. Antimicrob. Agents Chemother. 47:3008-3011. - PMC - PubMed
    1. Hamamoto, K., T. Shimizu, N. Fujimoto, Y. Zhang, and S. Arai. 2001. In vitro activities of moxifloxacin and other fluoroquinolones against Mycoplasma pneumoniae. Antimicrob. Agents Chemother. 45:1908-1910. - PMC - PubMed
    1. Kenny, G. E., T. M. Hooton, M. C. Roberts, F. D. Cartwright, and J. Hoyt. 1989. Susceptibilities of genital mycoplasmas to the newer quinolones as determined by the agar dilution method. Antimicrob. Agents Chemother. 33:103-107. - PMC - PubMed

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