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Case Reports
. 2003 Dec;136(6):1159-61.
doi: 10.1016/s0002-9394(03)00635-4.

Acanthamoeba keratitis as a complication of orthokeratology

Sun Xuguang  1 , Chen Lin, Zhang Yan, Wang Zhiqun, Li Ran, Luo Shiyun, Jin Xiuying
Affiliations
Case Reports

Acanthamoeba keratitis as a complication of orthokeratology

Sun Xuguang et al. Am J Ophthalmol. 2003 Dec.

Abstract

Purpose: To present four cases of Acanthamoeba keratitis as a complication of orthokeratology.

Design: Observational case report.

Methods: Four patients with Acanthamoeba keratitis had histories of overnight orthokeratology lens wear of 6 months to 2 years.

Results: Three cases were diagnosed with Acanthamoeba keratitis by corneal scraping and one by confocal microscopy examination. The patients were treated with chlorhexidine, metronidazole, and neomycin sulfate, resulting in a rapid resolution of ocular inflammation.

Conclusion: Overnight wear of orthokeratology lenses may induce Acanthamoeba keratitis.

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