Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Jan;57(1):8-17.
doi: 10.1002/cm.10155.

The radial spokes and central apparatus: mechano-chemical transducers that regulate flagellar motility

Affiliations
Review

The radial spokes and central apparatus: mechano-chemical transducers that regulate flagellar motility

Elizabeth F Smith et al. Cell Motil Cytoskeleton. 2004 Jan.
No abstract available

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
A transverse view of a Chlamydomonas flagellum as viewed looking proximal to distal; the outer doublet microtubules are numbered according to Hoops and Witman [1983]. The direction of the effective stroke is indicated by the arrow. Only doublet number one lacks an outer dynein arm. A single doublet microtubule (doublet one) with associated radial spoke, as well as the entire central apparatus, is enlarged. The radial spoke diagram is further enlarged to include details of the possible location of particular radial spoke components. RSP2 serves as the primary stalk component and consists of GAF domains as well as calmodulin (CM) binding domains [Yang et al., 2002]. The central apparatus diagram is adapted from Mitchell and Sale [1999]. While PF6, PF16, PP1c, AKAP240, KRP, and KLP1 have been tentatively localized to specific central tubules (see Table I), it is unknown whether they localize to specific projections. Therefore, they are listed above the central apparatus diagram. For references, see Table I.

References

    1. Adams GM, Huang B, Piperno G, Luck DJ. Central-pair micro-tubular complex of Chlamydomonas flagella: polypeptide composition as revealed by analysis of mutants. J Cell Biol. 1981;91:69–76. - PMC - PubMed
    1. Afzelius BA. The immotile-cilia syndrome: a microtubule-associated defect. CRC Crit Rev Biochem. 1985;19:63–87. - PubMed
    1. Afzelius BA, Eliasson R. Flagellar mutants in man: on the heterogeneity of the immotile-cilia syndrome. J Ultrastruct Res. 1979;69:43–52. - PubMed
    1. Baccetti B, Burrini AG, Dallai R, Pallini V. The dynein electrophoretic bands in axonemes naturally lacking the inner or the outer arm. J Cell Biol. 1979;80:334–340. - PMC - PubMed
    1. Bannai H, Yoshimura M, Takahashi K, Shingyoji C. Calcium regulation of microtubule sliding in reactivated sea urchin sperm flagella. J Cell Sci. 2000;113:831–839. - PubMed

LinkOut - more resources