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Case Reports
. 2003 Nov;56(5):581-2.
doi: 10.1046/j.1365-2125.2003.01906.x.

Neonatal intraventricular haemorrhage associated with maternal use of paroxetine

Yvonne C M Duijvestijn  1 , Mathijs D Kalmeijer, Anneke L M Passier, Peter Dahlem, Frans Smiers
Affiliations
Case Reports

Neonatal intraventricular haemorrhage associated with maternal use of paroxetine

Yvonne C M Duijvestijn et al. Br J Clin Pharmacol. 2003 Nov.

Abstract

Selective serotonin reuptake inhibitors (SSRIs) have been reported to inhibit serotonin uptake into platelets, resulting in decreased platelet function. We report a case of a large intraventricular haemorrhage in a 6-h-old boy, whose mother used paroxetine during pregnancy.

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References

    1. Hergovich N, Aigner M, Eichler HG, Entlicher J, Drucker C, Jilma B. Paroxetine decreases platelet serotonin storage and platelet functions in human beings. Clin Pharmacol Ther. 2000;68:435–442. - PubMed
    1. Cooper TA, Valcour VG, Gibbons RB, O'Brien-Falls K. Spontaneous ecchymoses due to paroxetine administration. Am J Med. 1998;104:197–198. - PubMed
    1. Walraven C, Mamdani MM, Wells PS, Williams JI. Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: retrospective cohort study. BMJ. 2001;323:655–658. - PMC - PubMed
    1. Stanford MS, Patton JH. In utero exposure to fluoxetine HCl increases hematoma frequency at birth. Pharmacol Biochem Behav. 1993;45:959–962. - PubMed
    1. Nijhuis IJ, Kok-Van Rooij GW, Bosschaart AN. Withdrawal reactions of a premature neonate after maternal use of paroxetine. Arch Dis Child Fetal Neonatal. 2001;84:F77. - PMC - PubMed

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