doi: 10.4414/smw.2003.10228.
Monitoring of radiation-induced germline mutation in humans
Affiliations
- PMID: 14652802
- DOI: 10.4414/smw.2003.10228
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Monitoring of radiation-induced germline mutation in humans
Swiss Med Wkly.
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Abstract
Estimating the genetic hazards of radiation and other mutagens in humans depends on extrapolation from experimental systems. Recent data have shown that minisatellite loci provide a useful and sensitive experimental approach for monitoring radiation-induced mutation in humans. This review describes the progress made in validating this approach and presents the results of recent publications on the analysis of minisatellite mutation rates in the irradiated families.
Comment in
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Chernobyl--opening the pages to scientific authors from Eastern Europe.Swiss Med Wkly. 2003 Sep 6;133(35-36):473. doi: 10.4414/smw.2003.10437. Swiss Med Wkly. 2003. PMID: 14652801 No abstract available.