Case Reports
[Non-radioactive in situ hybridization of alpha-satellite sequences in cytogenetic diagnosis]
[Article in
Italian]
Affiliations
- PMID: 1465321
Item in Clipboard
Case Reports
[Non-radioactive in situ hybridization of alpha-satellite sequences in cytogenetic diagnosis]
[Article in
Italian]
Pathologica.
1992 May-Jun.
Abstract
Non isotopic in situ hybridization with alpha-satellite DNA probes in the cytogenetic diagnosis. Standard banding cytogenetic techniques do not always allow to define the structure and the origin of chromosome rearrangements involving the centromere region. Non-isotopic in situ hybridization of alphoid sequences has allowed to determine the origin of the centromeres in the metaphases of 5 patients referred to us for: 2 structural rearrangements involving chromosome 21, 2 structural rearrangements involving chromosome Y and 1 reciprocal translocation involving on chromosome 20 and one chromosome 15.
Similar articles
-
Fluorescence in situ hybridization (FISH) of a whole-arm translocation involving chromosomes 18 and 20 with alpha-satellite DNA probes: detection of a centromeric DNA break?Am J Med Genet. 1992 Oct 1;44(3):340-4. doi: 10.1002/ajmg.1320440314. Am J Med Genet. 1992. PMID: 1488982
-
Application of fluorescence in situ hybridization to the identification of different marker chromosomes.Ann Genet. 1998;41(1):5-10. Ann Genet. 1998. PMID: 9599644
-
Unique (Y;13) translocation in a male with oligozoospermia: cytogenetic and molecular studies.Eur J Hum Genet. 2002 Aug;10(8):467-74. doi: 10.1038/sj.ejhg.5200835. Eur J Hum Genet. 2002. PMID: 12111641
-
Coexistence of inverted Y, chromosome 15p+ and abnormal phenotype.Genet Couns. 1999;10(2):163-70. Genet Couns. 1999. PMID: 10422010 Review.
-
Molecular cytogenetic study of supernumerary marker chromosomes in an unselected group of children.Am J Med Genet. 1995 Mar 13;56(1):106-11. doi: 10.1002/ajmg.1320560124. Am J Med Genet. 1995. PMID: 7747772 Review.