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Comment
. 2003 Dec;73(6):1465-6.
doi: 10.1086/379745.

Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis

Dermot P B McGovern, David A Van Heel, Kenichi Negoro, Tariq Ahmad, Derek P Jewell
Comment

Further evidence of IBD5/CARD15 (NOD2) epistasis in the susceptibility to ulcerative colitis

Dermot P B McGovern et al. Am J Hum Genet. 2003 Dec.
No abstract available

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Comment on

References

Electronic-Database Information

    1. Online Mendelian Inheritance in Man (OMIM), http://www.ncbi.nlm.nih.gov/Omim/ (for Crohn disease, ulcerative colitis, IBD5, and CARD15 [NOD2])

References

    1. Armuzzi A, Ahmad T, Ling KL, De Silva A, Cullen S, Van Heel D, Orchard TR, Welsh KI, Marshall SE, Jewell DP (2003) Genotype-phenotype analysis of the Crohn’s disease susceptibility haplotype on chromosome 5q31. Gut 52:1133–113910.1136/gut.52.8.1133 - DOI - PMC - PubMed
    1. Bonen DK, Ogura Y, Nicolae DL, Inohara N, Saab L, Tanabe T, Chen FF, Foster SJ, Duerr RH, Brant SR, Cho JH, Nunez G (2003) Crohn’s disease-associated NOD2 variants share a signaling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology 124:140–14610.1053/gast.2003.50019 - DOI - PubMed
    1. Giallourakis C, Stoll M, Miller K, Hampe J, Lander ES, Daly MJ, Schreiber S, Rioux JD (2003) IBD5 is a general risk factor for inflammatory bowel disease: replication of association with Crohn disease and identification of a novel association with ulcerative colitis. Am J Hum Genet 73:205–211 - PMC - PubMed
    1. Mirza MM, Fisher SA, King K, Cuthbert AP, Hampe J, Sanderson J, Mansfield J, Donaldson P, Macpherson AJ, Forbes A, Schreiber S, Lewis CM, Mathew CG (2003) Genetic evidence for interaction of the 5q31 cytokine locus and the CARD15 gene in Crohn disease. Am J Hum Genet 72:1018–1022 - PMC - PubMed
    1. Negoro K, McGovern DP, Kinouchi Y, Takahashi S, Lench NJ, Shimosegawa T, Carey A, Cardon LR, Jewell DP, van Heel DA (2003) Analysis of the IBD5 locus and potential gene-gene interactions in Crohn’s disease. Gut 52:541–54610.1136/gut.52.4.541 - DOI - PMC - PubMed

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