Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel versus cisplatin and paclitaxel (GOG158) and an update on GOG0182-ICON5
- PMID: 14656272
- DOI: 10.1111/j.1525-1438.2003.13362.x
Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel versus cisplatin and paclitaxel (GOG158) and an update on GOG0182-ICON5
Abstract
Mature results from GOG158 have clearly established carboplatin and paclitaxel as an effective and well-tolerated standard regimen, providing a basis for the reference arm in GOG0182-ICON5, an ongoing multiarmed phase III trial of the Gynecologic Cancer InterGroup (GCIG) evaluating the incorporation of newer cytotoxic agents. Results from GOG158 will be reviewed, including an analysis of second-look surgical outcomes, followed by an update on the current status of GOG0182-ICON5.
Similar articles
-
Optimal therapy of advanced ovarian cancer: carboplatin and paclitaxel vs. cisplatin and paclitaxel (GOG 158) and an update on GOG0 182-ICON5.Int J Gynecol Cancer. 2003 Nov-Dec;13(6):735-40. doi: 10.1111/j.1525-1438.2003.13602.x. Int J Gynecol Cancer. 2003. PMID: 14675308 Clinical Trial.
-
Carboplatin versus cisplatin in ovarian cancer.Semin Oncol. 1995 Oct;22(5 Suppl 12):88-90. Semin Oncol. 1995. PMID: 7481869 Review.
-
Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group study.J Clin Oncol. 2003 Sep 1;21(17):3194-200. doi: 10.1200/JCO.2003.02.153. Epub 2003 Jul 14. J Clin Oncol. 2003. PMID: 12860964 Clinical Trial.
-
Paclitaxel (Taxol)/carboplatin combination chemotherapy in the treatment of advanced ovarian cancer.Semin Oncol. 2000 Jun;27(3 Suppl 7):3-7. Semin Oncol. 2000. PMID: 10952119 Review.
-
Current status of chemotherapy for ovarian cancer.Semin Oncol. 1995 Oct;22(5 Suppl 12):61-6. Semin Oncol. 1995. PMID: 7481863 Review.
Cited by
-
The Antineoplastic Effect of Carboplatin Is Potentiated by Combination with Pitavastatin or Metformin in a Chemoresistant High-Grade Serous Carcinoma Cell Line.Int J Mol Sci. 2022 Dec 21;24(1):97. doi: 10.3390/ijms24010097. Int J Mol Sci. 2022. PMID: 36613537 Free PMC article.
-
A Prognostic and Carboplatin Response Predictive Model in Ovarian Cancer: A Mono-Institutional Retrospective Study Based on Clinics and Pharmacogenomics.Biomedicines. 2022 May 23;10(5):1210. doi: 10.3390/biomedicines10051210. Biomedicines. 2022. PMID: 35625946 Free PMC article.
-
High-Grade Serous Ovarian Cancer: Basic Sciences, Clinical and Therapeutic Standpoints.Int J Mol Sci. 2019 Feb 22;20(4):952. doi: 10.3390/ijms20040952. Int J Mol Sci. 2019. PMID: 30813239 Free PMC article. Review.
-
Potent cytotoxic effects of Calomeria amaranthoides on ovarian cancers.J Exp Clin Cancer Res. 2011 Mar 14;30(1):29. doi: 10.1186/1756-9966-30-29. J Exp Clin Cancer Res. 2011. PMID: 21401934 Free PMC article.
-
Considering usual medical care in clinical trial design.PLoS Med. 2009 Sep;6(9):e1000111. doi: 10.1371/journal.pmed.1000111. Epub 2009 Sep 29. PLoS Med. 2009. PMID: 19787044 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical