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Review
. 2003;4(12):240.
doi: 10.1186/gb-2003-4-12-240. Epub 2003 Nov 18.

Localizing the proteome

Jeremy C Simpson  1 , Rainer Pepperkok
Affiliations
Review

Localizing the proteome

Jeremy C Simpson et al. Genome Biol. 2003.

Abstract

The subcellular localization of the entire proteome of an organism, the yeast Saccharomyces cerevisiae, has been revealed for the first time. Comparison with less comprehensive studies of mammalian cells provides insights into the localization of the mammalian proteome.

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Figures

Figure 1
Figure 1
Comparison of the distribution of GFP-tagged proteins to different subcellular organelles as determined in three different studies [9-11]. The percentage of proteins localizing to the cytoplasm, nucleus, endoplasmic reticulum (ER) and Golgi are shown as example compartments. The data are taken for yeast cells [10,11] and for mammalian cells [9]. In [10] Golgi localization was not determined.
See this image and copyright information in PMC

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