Where the rubber meets the road in pharmacogenetics: assessment of gene-environment interactions

Editorial

Elizabeth R Hauser et al. Am Heart J. 2003 Dec.

. 2003 Dec;146(6):929-31.

doi: 10.1016/S0002-8703(03)00502-7.

No abstract available

Comment on

The cholesteryl ester transfer protein Taq1B gene polymorphism predicts clinical benefit of statin therapy in patients with significant coronary artery disease.
Carlquist JF, Muhlestein JB, Horne BD, Hart NI, Bair TL, Molhuizen HO, Anderson JL. Carlquist JF, et al. Am Heart J. 2003 Dec;146(6):1007-14. doi: 10.1016/S0002-8703(03)00501-5. Am Heart J. 2003. PMID: 14660992

Re: "flexible matching strategies to increase power and efficiency to detect and estimate gene-environment interactions in case-control studies".
Schill W, Wild P. Schill W, et al. Am J Epidemiol. 2004 Jun 1;159(11):1107-8; author reply 1108. doi: 10.1093/aje/kwh144. Am J Epidemiol. 2004. PMID: 15155296 No abstract available.
Gene-environment interactions for complex traits: definitions, methodological requirements and challenges.
Dempfle A, Scherag A, Hein R, Beckmann L, Chang-Claude J, Schäfer H. Dempfle A, et al. Eur J Hum Genet. 2008 Oct;16(10):1164-72. doi: 10.1038/ejhg.2008.106. Epub 2008 Jun 4. Eur J Hum Genet. 2008. PMID: 18523454 Review.
Cancer pharmacogenetics.
Marsh S. Marsh S. Methods Mol Biol. 2008;448:437-46. doi: 10.1007/978-1-59745-205-2_15. Methods Mol Biol. 2008. PMID: 18370241
Consultants' forum: should post hoc sample size calculations be done?
Walters SJ. Walters SJ. Pharm Stat. 2009 Apr-Jun;8(2):163-9. doi: 10.1002/pst.334. Pharm Stat. 2009. PMID: 18416448
An introduction to sample size and power.
Bernstein BA. Bernstein BA. J Dev Behav Pediatr. 2008 Dec;29(6):516-22. doi: 10.1097/DBP.0b013e3181900224. J Dev Behav Pediatr. 2008. PMID: 19077847 Review. No abstract available.