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Case Reports
. 2003 Dec;41(12):5798-802.
doi: 10.1128/JCM.41.12.5798-5802.2003.

Extraintestinal pathogenic Escherichia coli as a cause of invasive nonurinary infections

James R Johnson  1 , Abby Gajewski, Alan J Lesse, Thomas A Russo
Affiliations
Case Reports

Extraintestinal pathogenic Escherichia coli as a cause of invasive nonurinary infections

James R Johnson et al. J Clin Microbiol. 2003 Dec.

Abstract

Multiple Escherichia coli isolates from four adults with extraintestinal infections underwent molecular phylotyping and virulence profiling. A patient with secondary peritonitis had two low-virulence E. coli strains from phylogenetic groups A and D. In contrast, three patients with invasive extraurinary infections (septic arthritis/pyomyositis, nontraumatic meningitis/hematogenous osteomyelitis, and pneumonia) each had a single high-virulence phylogenetic group B2 strain resembling typical isolates causing urinary infection and/or sepsis, i.e., extraintestinal pathogenic E. coli.

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Figures

FIG. 1.
FIG. 1.
Clinical and radiographic evidence of hematogenous osteomyelitis (case 3). (A) Ecchymosis with associated swelling is evident over the proximal interphalangeal joint of the left index finger. (B) Underlying bony destruction consistent with osteomyelitis is apparent radiographically (white arrows).
FIG. 2.
FIG. 2.
RAPD profiles of 10 Escherichia coli isolates from four patients with serious extraintestinal E. coli infections. Case and strain number are indicated above each sample lane (lanes 2 to 11). Lane numbers are shown at bottom. Lanes 1 and 12, 250-bp ladder.
See this image and copyright information in PMC

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