Conservative treatment may be beneficial for young women with atypical endometrial hyperplasia or endometrial adenocarcinoma

Abstract

Objective: To evaluate whether an alternative treatment to radical hysterectomy exists for young women with endometrial adenocarcinoma.

Design: A review of the literature (70 articles) plus personal results.

Setting: University hospital.

Patient(s): Women with atypical endometrial hyperplasia or adenocarcinoma.

Main outcome measure(s): The recurrence rate and the pregnancy rate after conservative therapy.

Conclusion(s): Conservative treatment of well-differentiated stage I endometrial adenocarcinoma can be considered in young patients, with close surveillance to diagnose any possible recurrence.