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. 2004 Jan 1;32(Database issue):D459-62.
doi: 10.1093/nar/gkh137.

MitoP2, an integrated database on mitochondrial proteins in yeast and man

C Andreoli  1 , H Prokisch, K Hörtnagel, J C Mueller, M Münsterkötter, C Scharfe, T Meitinger
Affiliations

MitoP2, an integrated database on mitochondrial proteins in yeast and man

C Andreoli et al. Nucleic Acids Res. .

Abstract

The aim of the MitoP2 database (http://ihg.gsf.de/mitop2) is to provide a comprehensive list of mitochondrial proteins of yeast and man. Based on the current literature we created an annotated reference set of yeast and human proteins. In addition, data sets relevant to the study of the mitochondrial proteome are integrated and accessible via search tools and links. They include computational predictions of signalling sequences, and summarize results from proteome mapping, mutant screening, expression profiling, protein-protein interaction and cellular sublocalization studies. For each individual approach, specificity and sensitivity for allocating mitochondrial proteins was calculated. By providing the evidence for mitochondrial candidate proteins the MitoP2 database lends itself to the genetic characterization of human mitochondriopathies.

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Figures

Figure 1
Figure 1
Search mask for mitochondrial proteins in yeast. Datasets can be selected from high-throughput experiments and in silico predictions.
Figure 2
Figure 2
Search mask for mitochondrial proteins in man. Datasets can be selected from high-throughput experiments and in silico predictions.
See this image and copyright information in PMC

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