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Review
. 2004 Jan;4(1):74-80.
doi: 10.1007/s11910-004-0016-6.

Spinal muscular atrophy

Susan T Iannaccone  1 , Stephen A Smith, Louise R Simard
Affiliations
Review

Spinal muscular atrophy

Susan T Iannaccone et al. Curr Neurol Neurosci Rep. 2004 Jan.

Abstract

Spinal muscular atrophy is a common genetic disease of the motor neuron (frequency of eight cases per 100,000 live births) with a high mortality during infancy and no known treatment. Death is caused by severe and progressive restrictive lung disease. New information regarding the nature and function of the SMN protein and the availability of new pharmacologic agents now make it possible to consider clinical trials in this disease. Rehabilitation and proper management of medical complications have improved both the quality and duration of life for children with spinal muscular atrophy.

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References

    1. Muscle Nerve. 1990;13 Suppl:S11-2 - PubMed
    1. Muscle Nerve. 2003 Oct;28(4):432-7 - PubMed
    1. Arch Neurol. 2003 Aug;60(8):1130-6 - PubMed
    1. Neuropediatrics. 1996 Feb;27(1):8-15 - PubMed
    1. Hum Mutat. 2000;15(3):228-37 - PubMed

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