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Review
. 2004 Jan 9;313(2):447-52.
doi: 10.1016/j.bbrc.2003.07.020.

Amino acids as regulators of gene expression: molecular mechanisms

Céline Jousse  1 , Julien Averous, Alain Bruhat, Valérie Carraro, Sylvie Mordier, Pierre Fafournoux
Affiliations
Review

Amino acids as regulators of gene expression: molecular mechanisms

Céline Jousse et al. Biochem Biophys Res Commun. .

Abstract

Regulation of gene expression by nutrients in mammals is an important mechanism allowing them to adapt their physiological functions according to the supply of nutrient in the diet. It has been shown recently that amino acids are able to regulate by themselves the expression of numerous genes. CHOP, asparagine synthetase, and IGFBP-1 regulation following AA starvation will be described in this review with special interest in the molecular mechanisms involved.

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