Review
doi: 10.1016/j.cellsig.2003.08.011.
Signal transduction of bone morphogenetic protein receptors
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- PMID: 14687659
- DOI: 10.1016/j.cellsig.2003.08.011
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Review
Signal transduction of bone morphogenetic protein receptors
Cell Signal.
2004 Mar.
Abstract
Bone morphogenetic proteins (BMPs) play a crucial role during all stages of embryonic development. Although only two major signaling pathways have been characterized (the p38 and Smad pathways), the BMP signaling is complex and includes several negative feedback mechanisms. This article reviews the current state of BMP receptor signaling and provides a summary of the crosstalk of the BMP receptor pathway with other major signaling pathways.
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