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. 2004 Jan;48(1):358-9.
doi: 10.1128/AAC.48.1.358-359.2004.

Sequencing of Neisseria meningitidis penA gene: the key to success in defining penicillin G breakpoints

Luisa Arreaza  1 , Celia Salcedo, Belén Alcalá, María José Uría, Raquel Abad, Rocío Enríquez, Julio A Vázquez
Affiliations

Sequencing of Neisseria meningitidis penA gene: the key to success in defining penicillin G breakpoints

Luisa Arreaza et al. Antimicrob Agents Chemother. 2004 Jan.

Abstract

Testing of susceptibility to penicillin G by E-test and sequencing of an internal fragment of the penA gene were done for 43 meningococcal strains. Those strains for which the MIC was >/=0.094 micro g/ml showed mosaic alleles, so 0.094 micro g/ml is suggested as the penicillin G intermediate breakpoint when E-test is used.

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References

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