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Comparative Study
. 2003 Dec;4(6):717-22.
doi: 10.1016/j.yebeh.2003.09.008.

Mesial temporal lobe epilepsy and hippocampal sclerosis: cognitive function assessment in Hispanic patients

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Comparative Study

Mesial temporal lobe epilepsy and hippocampal sclerosis: cognitive function assessment in Hispanic patients

Silvia Oddo et al. Epilepsy Behav. 2003 Dec.

Erratum in

  • Epilepsy Behav. 2006 Aug;9(1):215. Silvia, Oddo [corrected to Oddo, Silvia]; Patricia, Solís [corrected to Solís, Patricia]; Damián, Consalvo [corrected to Consalvo, Damián]; Brenda, Giagante [corrected to Giagante, Brenda]; Walter, Silva [corrected to Silva, Walter]; Luciana, D'Alessio

Abstract

Purpose: The goal of this study was to assess the cognitive function status in patients with mesial temporal lobe epilepsy and hippocampal sclerosis (TLE+HS) to determine their cognitive function profile and to correlate material-specific memory deficits with HS laterality diagnosed by MRI.

Methods: Seventy-one patients were assessed with a neuropsychological protocol that includes IQ, attention, handedness, verbal memory, visual memory, language, and the executive function. chi(2) and correlation tests were used.

Results: Memory impairment was found in 46 patients (66%): patients without any memory deficit (n=25), patients with verbal memory deficit (n=21), patients with visual memory deficit (n=17), patients with deficit for both types of memory (n=8). Correlation between MRI lesion and memory was 66%. Language was impaired in 33 patients (46%). Eighteen patients (25%) had a deficit of the executive function.

Conclusions: Patients with TLE+HS presented with a deficit in material-specific episodic memory correlating in large proportion with HS lateralization. We also found language and executive function impairments.

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