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. 2004 Jan 8;6(1):35-8.
doi: 10.1021/ol035985e.

Arylation of heterocycles via rhodium-catalyzed C-H bond functionalization

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Arylation of heterocycles via rhodium-catalyzed C-H bond functionalization

Jared C Lewis et al. Org Lett. .

Abstract

[reaction: see text] A new method for the rhodium-catalyzed arylation of a variety of heterocycles has been developed. The reaction provided moderate to good yields of the arylated products. A preliminary mechanistic investigation of this reaction revealed the intermediacy of an isolable N-heterocyclic carbene complex.

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