Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2004 Jan 8;6(1):103-6.
doi: 10.1021/ol0361397.

Enantioselective preparation of the C1-C11 fragment of apoptolidin

William D Paquette  1 , Richard E Taylor
Affiliations

Enantioselective preparation of the C1-C11 fragment of apoptolidin

William D Paquette et al. Org Lett. .

Abstract

[reaction: see text] A novel approach toward the synthesis of the triene portion of the biologically active polyketide apoptolidin is described. The use of an iterative thionyl chloride rearrangement/oxidation sequence to construct trisubstituted olefins is explored.

PubMed Disclaimer

Publication types

LinkOut - more resources