No T without D3: a critical role for cyclin D3 in normal and malignant precursor T cells
- PMID: 14706330
- DOI: 10.1016/s1535-6108(03)00305-2
No T without D3: a critical role for cyclin D3 in normal and malignant precursor T cells
Abstract
A definitive knockout reported in this issue of Cancer Cell by Sicinska et al. reveals an unsuspected role for cyclin D3 in normal T cell development and suggests new therapeutic possibilities in precursor T cell leukemia.
Comment on
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Requirement for cyclin D3 in lymphocyte development and T cell leukemias.Cancer Cell. 2003 Dec;4(6):451-61. doi: 10.1016/s1535-6108(03)00301-5. Cancer Cell. 2003. PMID: 14706337
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