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Comment
. 2004 Jan 13;101(2):417-8.
doi: 10.1073/pnas.0308043101. Epub 2004 Jan 5.

A myristoyl switch regulates membrane binding of HIV-1 Gag

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Comment

A myristoyl switch regulates membrane binding of HIV-1 Gag

Marilyn D Resh. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Fig. 1.
Fig. 1.
Structure of the HIV-1 Gag protein. (A) A schematic representation of Pr55gag and its sub-domains. (B) The entropic myristoyl switch for myrMA as proposed by Tang et al. (11). Note that ∼40% of the myristate moiety remains exposed in the myr(s) state.
Fig. 2.
Fig. 2.
Regulation of the myristoyl switch during the HIV-1 life cycle. A schematic representation of Gag is shown at the late stages of infection (A), in the virion (B), and in the newly infected cell (C).

Comment on

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