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Review
. 1992 Dec;17(12):498-501.
doi: 10.1016/0968-0004(92)90339-b.

14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins

A Aitken  1 , D B Collinge, B P van Heusden, T Isobe, P H Roseboom, G Rosenfeld, J Soll
Affiliations
Review

14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins

A Aitken et al. Trends Biochem Sci. 1992 Dec.

Abstract

A family of proteins known as 14-3-3 is currently receiving increased attention by investigators studying a broad range of biological systems, including plants and invertebrates. The outstanding feature of this family is the extraordinarily high sequence conservation observed. Current thinking indicates that these proteins may function as regulators in signal transduction/phosphorylation mechanisms.

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