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Review
. 2003:231:197-258.
doi: 10.1016/s0074-7696(03)31005-8.

Regulation by RNA

Maciej Szymański  1 , Jan Barciszewski
Affiliations
Review

Regulation by RNA

Maciej Szymański et al. Int Rev Cytol. 2003.

Abstract

In recent years, noncoding RNAs (ncRNAs) have been shown to constitute key elements implicated in a number of regulatory mechanisms in the cell. They are present in bacteria and eukaryotes. The ncRNAs are involved in regulation of expression at both transcriptional and posttranscriptional levels, by mediating chromatin modifications, modulating transcription factor activity, and influencing mRNA stability, processing, and translation. Noncoding RNAs play a key role in genetic imprinting, dosage compensation of X-chromosome-linked genes, and many processes of differentiation and development.

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