Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2003 Nov;20(11):444-8.
doi: 10.1023/b:jarg.0000006705.46147.a2.

Analyzing factors affecting the success rate of frozen-thawed embryos

Affiliations

Analyzing factors affecting the success rate of frozen-thawed embryos

S Lahav-Baratz et al. J Assist Reprod Genet. 2003 Nov.

Abstract

Purpose: In recent years the infertile population applying for IVF treatments was changed and so the indications for performing intracellular sperm injection (ICSI). The aim of this study was to analyze predicting factors of our thawing cycles.

Methods: From December 1998 to July 2001, 440 consecutive thawing cycles were performed. Patient characteristics were examined. The number of cryopreserved embryos, number of transferred embryos, the timing of cryopreservation (48 h vs. 72 h), and embryo survival rate were analyzed as a possible predictor for pregnancies achievement.

Results: Conventional IVF patient's characteristic was significantly different from ICSI population and analysis has been performed for every population separately. In the IVF population the women age, the number of transferred embryos, and timing of cryopreservation were factors significantly influencing the pregnancy rate. Interestingly, in the ICSI population only the number of transferred embryos was found to be a predictive factor.

Conclusion: ICSI and IVF cycles should be analyzed separately. Not all the factors influencing the success rate in the conventional IVF population are valid in the ICSI population.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Trounson A, Mohr L. Human pregnancy following cryopreservation, thawing and transfer of an eight-cell embryo. Nature. 1983;305:707–709. - PubMed
    1. Testart J, Lassalle B, Belaisch-Allart J, Hazout A, Forman R, Rainborn JD, Frydman R. High pregnancy rate after early human embryo freezing. Fertil Steril. 1986;46:268–272. - PubMed
    1. Camus M, Van Den Abbeel E, Van Waesberghe L, Wisanto A, Devroey P, Van Steirteghem AC. Human viability after freezing with dimethylsulfoxide as a cryoprotectant. Fertil Steril. 1989;51:460–465. - PubMed
    1. Van Der Elts J, Van Den Abbeel E, Vitrier S, Camus M, Devroey P, Van Steirteghem AC. Selective transfer of cryopreserved human embryos with further cleavage after thawing increases delivery and implantation rates. Hum Reprod. 1997;12:1513–1521. - PubMed
    1. Shapiro BS, Harris DC, Richter KS. Predictive value of 72-hour blastomere cell number on blastocyst development and success of subsequent transfer based on the degree of blastocyst development. Fertil Steril. 2000;73:582–586. - PubMed