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. 2004 Jan 15;93(2):234-7.
doi: 10.1016/j.amjcard.2003.09.050.

Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction

J Eduardo Rame  1 , Marlon Ramilo, Nali Spencer, Christopher Blewett, Sameer K Mehta, Daniel L Dries, Mark H Drazner
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Development of a depressed left ventricular ejection fraction in patients with left ventricular hypertrophy and a normal ejection fraction

J Eduardo Rame et al. Am J Cardiol. .

Abstract

The progression from concentric left ventricular (LV) hypertrophy to heart failure has not been well defined. Of 159 predominantly hypertensive African-American patients with LV hypertrophy and a normal ejection fraction (EF), 28 (18%) developed a reduced EF after a median follow-up of approximately 4 years. Risk factors for this outcome included a history of coronary artery disease, pulmonary edema seen on a chest x-ray, or a subsequent myocardial infarction.

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