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. 2004 Jan;42(1):431-4.
doi: 10.1128/JCM.42.1.431-434.2004.

Molecular epidemiology of disease due to Mycobacterium bovis in humans in the United Kingdom

Andrea L Gibson  1 , Glyn Hewinson, Tony Goodchild, Brian Watt, Alistair Story, Jacqueline Inwald, Francis A Drobniewski
Affiliations

Molecular epidemiology of disease due to Mycobacterium bovis in humans in the United Kingdom

Andrea L Gibson et al. J Clin Microbiol. 2004 Jan.

Abstract

Mycobacterium bovis is the causative agent of bovine tuberculosis, with a wide host range. Fifty human M. bovis isolates were typed using spoligotyping and variable number tandem repeats (VNTR). Fifteen of these spoligotypes have not yet been recorded in cattle. The predominant spoligotype in humans and cattle was subdivided by VNTR.

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Figures

FIG. 1.
FIG. 1.
Spoligotyping patterns for human M. bovis isolates in the United Kingdom. Symbols: *, comparison of human M. bovis spoligotypes with a bank of M. bovis spoligotypes seen in United Kingdom cattle; **, international spoligotype website is http://www.Mbovis.org; _T arbitrarily labeled clusters. Superscript numbers: a, most predominant spoligotype (type 9); b, spoligotype not seen in United Kingdom cattle before; c, identical to type 9 except for absence of spacer 15.
FIG. 2.
FIG. 2.
Number of M. bovis cases by age group.
See this image and copyright information in PMC

References

    1. Aranaz, A., E. Liebana, A. Mateos, L. Dominguez, D. Vidal, M. Domingo, O. Gonzolez, E. F. Rodriguez-Ferri, A. E. Bunschoten, J. D. van Embden, and D. Cousins. 1996. Spacer oligonucleotide typing of Mycobacterium bovis strains from cattle and other animals: a tool for studying epidemiology of tuberculosis. J. Clin. Microbiol. 34:2734-2740. - PMC - PubMed
    1. Brosch, R., S. V. Gordon, M. Marmiesse, P. Brodin, C. Buchrieser, K. Eiglmeier, T. Garnier, C. Gutierrez, G. Hewinson, K. Kremer, L. M. Parsons, A. S. Pym, S. Samper, D. van Soolingen, and S. T. Cole. 2002. A new evolutionary scenario for the Mycobacterium tuberculosis complex. Proc. Natl. Acad. Sci. USA 99:3684-3689. - PMC - PubMed
    1. Clifton-Hadley, R. S., J. W. Wilesmith, M. S. Richards, P. Upton, and S. Johnston. 1995. The occurrence of Mycobacterium bovis infection in cattle in and around an area subject to extensive badger (Meles meles) control. Epidemiol. Infect. 114:179-193. - PMC - PubMed
    1. Communicable Disease Report Weekly. 1998. Enhanced surveillance of Mycobacterium bovis in humans. Commun. Dis. Rep. Wkly. 8:281, 284. - PubMed
    1. Communicable Disease Report Weekly. 2001. Enhanced surveillance of Mycobacterium bovis disease in humans in England and Wales from January 2001. Commun. Dis. Rep. Wkly. 11:2-3. - PubMed

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