Old drugs, new tricks: using genetically sensitized yeast to reveal drug targets
- PMID: 14718160
- DOI: 10.1016/s0092-8674(03)01070-5
Old drugs, new tricks: using genetically sensitized yeast to reveal drug targets
Abstract
A study in this issue of Cell illustrates the power of applying genomic approaches with model systems to characterize the biological activity of small molecules and to identify their cellular targets, which can clarify the mode of action of human therapeutics.
Comment on
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Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes.Cell. 2004 Jan 9;116(1):121-37. doi: 10.1016/s0092-8674(03)01035-3. Cell. 2004. PMID: 14718172
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