Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1992;252(2):99-102.
doi: 10.1007/BF02389635.

Treatment of lymphangioleiomyomatosis by ovariectomy, interferon alpha 2b and tamoxifen--a case report

M Klein  1 , O Krieger, R Ruckser, A Rosen, R Waldner, P Preis, A Beck
Affiliations
Case Reports

Treatment of lymphangioleiomyomatosis by ovariectomy, interferon alpha 2b and tamoxifen--a case report

M Klein et al. Arch Gynecol Obstet. 1992.

Abstract

The gender-specific prevalence of lymphangioleiomyomatosis (LAM) in premenopausal women suggests a hormonal etiology. Despite the antiestrogenic treatment (ovariectomy, tamoxifen) this disease is often refractory to therapy and almost inevitably leads to the patient's death. We describe a case where the antiproliferative effect of systemically applied interferon alpha 2b was successfully employed in addition to ovariectomy and the patient reached complete remission.

PubMed Disclaimer

References

    1. Semin Hematol. 1990 Jul;27(3 Suppl 4):15-22 - PubMed
    1. Chest. 1984 Jun;85(6):796-9 - PubMed
    1. Br J Haematol. 1991 Oct;79 Suppl 1:38-41 - PubMed
    1. N Engl J Med. 1990 Nov 1;323(18):1254-60 - PubMed
    1. AJR Am J Roentgenol. 1989 May;152(5):961-4 - PubMed

Publication types