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. 1992 Dec 15;44(12):2425-6.
doi: 10.1016/0006-2952(92)90692-c.

Activation of aldehyde dehydrogenase at physiological temperatures

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Activation of aldehyde dehydrogenase at physiological temperatures

J P Hill et al. Biochem Pharmacol. .

Abstract

The release of NADH from the enzyme.NADH complexes was rate limiting at 37 degrees, for the oxidation of propionaldehyde by sheep liver cytosolic aldehyde dehydrogenase. Marked substrate activation was observed at this temperature as was activation by p-(chloromercuri)benzoate. Activation of enzymic activity may be of importance in vivo.

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