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Comparative Study
. 2003;22(4):13-25.
doi: 10.1300/j069v22n04_03.

The use of tramadol for acute heroin withdrawal: a comparison to clonidine

Paul W Sobey  1 , Theodore V Parran Jr, Scott F Grey, Christopher L Adelman, Jaehak Yu
Affiliations
Comparative Study

The use of tramadol for acute heroin withdrawal: a comparison to clonidine

Paul W Sobey et al. J Addict Dis. 2003.

Abstract

Using a retrospective chart review, 59 patients detoxified with tramadol were compared to 85 patients detoxified with clonidine on rates of leaving against medical advice (AMA) and control of withdrawal symptoms. Patients detoxified with tramadol had 23% (95% CI, 0.09-0.59; P < .01) the risk of leaving AMA and scored an average of 0.24 points lower (95% CI, 0.08-0.41; P < .01) on a 0-3 point withdrawal symptom scale compared to patients detoxified with clonidine. This preliminary study indicates that tramadol is more effective in managing withdrawal than clonidine, and may be especially useful in outpatient detoxification.

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Comment in

  • The emperor' s new clothes.
    Schnoll SH. Schnoll SH. J Addict Dis. 2003;22(4):1-4. doi: 10.1300/j069v22n04_01. J Addict Dis. 2003. PMID: 14723473 No abstract available.

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