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. 2004 Jan 15;12(2):319-26.
doi: 10.1016/j.bmc.2003.11.005.

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity

John W Clader  1 , William Billard, Herbert Binch 3rd, Lian-Yong Chen, Gordon Crosby Jr, Ruth A Duffy, Jennifer Ford, Joseph A Kozlowski, Jean E Lachowicz, Shengjian Li, Charles Liu, Stuart W McCombie, Susan Vice, Gowei Zhou, William J Greenlee
Affiliations

Muscarinic M2 antagonists: anthranilamide derivatives with exceptional selectivity and in vivo activity

John W Clader et al. Bioorg Med Chem. .

Abstract

Anthranilamide analogues such as 23 are potent and highly selective muscarinic M2 antagonists that also show good oral bioavailability and in vivo activity.

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