Drug immunosuppression therapy for adult heart transplantation. Part 2: clinical applications and results
- PMID: 14726105
- DOI: 10.1016/j.athoracsur.2003.07.007
Drug immunosuppression therapy for adult heart transplantation. Part 2: clinical applications and results
Abstract
This review describes the clinical application of classical immunosuppressive drugs as well as that of more recent drugs. All current immunosuppressive drugs target T-cell activation, and cytokine production and clonal expansion, or both. Immunosuppressive protocols can be broadly divided into induction therapy, maintenance immunosuppression, and treatment of acute rejection episodes.
Similar articles
-
Drug immunosuppression therapy for adult heart transplantation. Part 1: immune response to allograft and mechanism of action of immunosuppressants.Ann Thorac Surg. 2004 Jan;77(1):354-62. doi: 10.1016/j.athoracsur.2003.07.006. Ann Thorac Surg. 2004. PMID: 14726104 Review.
-
Immunosuppression following cardiac transplantation.Cardiol Clin. 1990 Feb;8(1):83-96. Cardiol Clin. 1990. PMID: 2407363 Review.
-
[Immunosuppressive guidelines. The differences and advantages].Rev Esp Cardiol. 1995;48 Suppl 7:71-6. Rev Esp Cardiol. 1995. PMID: 8775820 Review. Spanish.
-
Immunosuppressive therapies after heart transplantation--The balance between under- and over-immunosuppression.Transplant Rev (Orlando). 2015 Jul;29(3):181-9. doi: 10.1016/j.trre.2015.02.005. Epub 2015 Feb 28. Transplant Rev (Orlando). 2015. PMID: 25812489 Review.
-
[Immunosuppression in organ transplantation. New substances and therapeutic approaches].Internist (Berl). 1996 Mar;37(3):229-39. Internist (Berl). 1996. PMID: 8919940 Review. German. No abstract available.
Cited by
-
Immunosuppressive T-cell antibody induction for heart transplant recipients.Cochrane Database Syst Rev. 2013 Dec 2;2013(12):CD008842. doi: 10.1002/14651858.CD008842.pub2. Cochrane Database Syst Rev. 2013. PMID: 24297433 Free PMC article.
-
Strategies to modulate immune responses: a new frontier for gene therapy.Mol Ther. 2009 Sep;17(9):1492-503. doi: 10.1038/mt.2009.150. Epub 2009 Jul 7. Mol Ther. 2009. PMID: 19584819 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical