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Comparative Study
. 1992;3(3):177-9.
doi: 10.3109/10425179209034013.

The HIT protein family: a new family of proteins present in prokaryotes, yeast and mammals

B Séraphin  1
Affiliations
Comparative Study

The HIT protein family: a new family of proteins present in prokaryotes, yeast and mammals

B Séraphin. DNA Seq. 1992.

Abstract

By comparing the sequence of a putative translation product from a Saccharomyces cerevisiae split gene with several data-bases, I have uncovered a new protein family. Members of this family are found in prokaryotes as well as in lower and higher eukaryotes. The function of these proteins is unknown but they share a characteristic histidine triad that may be involved in zinc binding. This group of protein has been named the HIT protein family.

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