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. 2004 Jan;9(1):34-8.
doi: 10.1111/j.1542-474x.2004.91529.x.

Increased P wave dispersion and maximum P wave duration after hemodialysis

Ugur K Tezcan  1 , Basri Amasyali, Ilknur Can, Kudret Aytemir, Sedat Köse, Izzet Yavuz, Hurkan Kursaklioglu, Ersoy Işik, Ertan Demirtaş, Ali Oto
Affiliations

Increased P wave dispersion and maximum P wave duration after hemodialysis

Ugur K Tezcan et al. Ann Noninvasive Electrocardiol. 2004 Jan.

Abstract

Background: Atrial fibrillation is a frequent arrhythmia in patients undergoing hemodialysis. The consequences of hemodialysis on P wave durations and P wave dispersion have not been fully understood. The objective of this study was to study the effect of dialysis on P wave maximum (Pmax), P wave minimum (Pmin), and P wave dispersion (Pd).

Methods: We studied Pmax, Pmin, and Pd in 32 patients (17 men and 15 women, mean age 54 +/- 18 years) with chronic renal failure undergoing hemodialysis. The difference between maximum and minimum P wave duration was calculated and defined as P wave dispersion (Pd= Pmax- Pmin).

Results: There was a significant increase in Pmax at the end of dialysis compared to the beginning (98 +/- 13 ms vs. 125 +/- 12 ms, P < 0.001). Pmin did not show any significant change (71 +/- 11 ms vs. 73 +/- 10 ms, P = 0.42). Pd was significantly increased at the end of dialysis (27 +/- 9 ms vs. 52 +/- 11 ms, P < 0.001). There was a negative correlation between serum potassium, magnesium, phosphate, blood urea nitrogen, and creatinin at the end of dialysis and Pmax and Pd, respectively (P < 0.05). A weak positive correlation was found between serum calcium, bicarbonate at the end of dialysis and Pmax and Pd (P < 0.05).

Conclusion: Hemodialysis ends with significant increase in P wave maximum duration and P wave dispersion, which might be responsible for the increased occurrence of atrial fibrillation in these groups of patients.

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Figures

Figure 1
Figure 1
Mean values of P wave durations and P dispersion (HD = hemodialysis).
See this image and copyright information in PMC

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