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. 1993 Jun;3(6):191-7.
doi: 10.1016/0962-8924(93)90213-k.

The oligodendrocyte and its many cellular processes

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The oligodendrocyte and its many cellular processes

S E Pfeiffer et al. Trends Cell Biol. 1993 Jun.

Abstract

The oligodendrocyte (OL) is increasingly providing a model system for probing central issues of cell biology. During development, OL progenitors undergo controlled migration, proliferation and differentiation, secrete and respond to a number of growth factors, and dramatically change their cellular architecture, culminating in the formation of the myelin sheath. This review examines some facets of the OL that make it an especially attractive tool for studying many basic questions in cell biology.

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