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Case Reports
. 2004 Feb;88(2):305-6.
doi: 10.1136/bjo.2003.024299.

Effect of docosahexaenoic acid supplementation on retinal function in a patient with autosomal dominant Stargardt-like retinal dystrophy

I M MacDonald, M Hébert, R J Yau, S Flynn, J Jumpsen, M Suh, M T Clandinin
Case Reports

Effect of docosahexaenoic acid supplementation on retinal function in a patient with autosomal dominant Stargardt-like retinal dystrophy

I M MacDonald et al. Br J Ophthalmol. 2004 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Fundus photograph of 15 year old patient at baseline examination.
Figure 2
Figure 2
Effect of DHA on retinal function in patient with ELOVL4 mutation.
See this image and copyright information in PMC

References

    1. Zhang K, Kniazeva M, Han M, et al. A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy. Nat Genet 2001;27:89–93. - PubMed
    1. Salem N Jr, Wegher B, et al. Arachidonic and docosahexaenoic acids are biosynthesized from their 18-carbon precursors in human infants. Proc Natl Acad Sci USA 1996;93:49–54. - PMC - PubMed
    1. Mackenzie PJ, Chang TS, Scott IU, et al. Assessment of vision-related function in patients with age-related macular degeneration. Ophthalmology 2002;109:720–9. - PubMed
    1. Hargreaves KM, Clandinin MT. Phosphatidylethanolamine methyltransferase: evidence for influence of diet fat on selectivity of substrate for methylation in rat brain synaptic plasma membranes. Biochim Biophys Acta 1987;918:97–105. - PubMed