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Case Reports
. 2003 Oct;14(4):279-81.
doi: 10.1080/jmf.14.4.279.281.

Twin-twin transfusion syndrome in a dizygotic monochorionic-diamniotic twin pregnancy

R A Quintero  1 , O T Mueller, J M Martínez, J Arroyo, E Gilbert-Barness, D Hilbelink, P Papenhausen, M Sutcliffe
Affiliations
Case Reports

Twin-twin transfusion syndrome in a dizygotic monochorionic-diamniotic twin pregnancy

R A Quintero et al. J Matern Fetal Neonatal Med. 2003 Oct.

Abstract

We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable pericentromeric markers was consistent with dispermic fertilization of two separate ova. This suggests that monochorionicity, rather than zygosity, may be responsible for the development of placental vascular anastomoses.

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