Insertion of mirena after endometrial resection in patients with adenomyosis

Abstract

Study objective: To evaluate the efficacy of Mirena, a levonorgestrel-releasing intrauterine device, after endometrial resection for treatment of menorrhagia caused by adenomyosis.

Design: Open, randomized, observational study (Canadian Task Force classification II-2).

Setting: Private hospital.

Patients: Ninety-five women.

Intervention: Endometrial resection, after which control patients received no further treatment and study patients had Mirena inserted immediately after the procedure.

Measurements and main results: The rate of amenorrhea after 1 year was significantly higher in the Mirena group. Nineteen percent of women in the control group had a second procedure to control bleeding compared with none in the Mirena group.

Conclusion: Insertion of Mirena after endometrial resection is effective treatment for menorrhagia caused by adenomyosis and has very few adverse effects.