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. 2003 Dec;69(6):593-600.

Adaptation of a strain of Plasmodium falciparum from Ghana to Aotus lemurinus griseimembra, A. nancymai, and A. vociferans monkeys

Joann S Sullivan  1 , James J Sullivan, Allison Williams, Katharine K Grady, Amy Bounngaseng, Curtis S Huber, Douglas Nace, Tyrone Williams, G Gale Galland, John W Barnwell, William E Collins
Affiliations
  • PMID: 14740874

Adaptation of a strain of Plasmodium falciparum from Ghana to Aotus lemurinus griseimembra, A. nancymai, and A. vociferans monkeys

Joann S Sullivan et al. Am J Trop Med Hyg. 2003 Dec.

Abstract

A strain of Plasmodium falciparum from Ghana was adapted to Aotus lemurinus griseimembra, A. nancymai, and A. vociferans monkeys. Gametocytes in splenectomized A. nancymai were infective to Anopheles freeborni mosquitoes. Sporozoite transmission was accomplished in two splenectomized A. nancymai with prepatent periods of 22 and 25 days. The Ghana III/CDC strain of P. falciparum is susceptible to treatment with chloroquine and mefloquine.

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