Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2004 Feb;32(Pt 1):65-9.
doi: 10.1042/bst0320065.

Membrane cholesterol and the regulation of signal transduction

C J Fielding  1 , P E Fielding
Affiliations
Review

Membrane cholesterol and the regulation of signal transduction

C J Fielding et al. Biochem Soc Trans. 2004 Feb.

Abstract

The plasma membrane of mammalian cells consists of microdomains differing in lipid and protein composition. Two distinct classes of cholesterol/sphingolipid microdomain (caveolae and lipid rafts) are assembly points for transmembrane signalling complexes. Recent evidence suggests that transient changes in cholesterol content may be important in regulating signal transduction.

PubMed Disclaimer

Publication types

LinkOut - more resources