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Review
. 2003 Dec;38(12):1275-8.
doi: 10.1080/00365520310005712.

Gastrointestinal complications of von Recklinghausen's disease: two case reports and a review of the literature

I Pinsk  1 , O Dukhno, A Ovnat, I Levy
Affiliations
Review

Gastrointestinal complications of von Recklinghausen's disease: two case reports and a review of the literature

I Pinsk et al. Scand J Gastroenterol. 2003 Dec.

Abstract

There are few reports of the association between neurofibromatosis (von Recklinghausen's disease) and large, solid stromal tumours of the gastrointestinal tract. The prevalence of gastrointestinal involvement in von Recklinghausen's disease has been estimated at 11%-25%. Some associated gastrointestinal stromal tumours present clinically as bowel obstruction, perforation or gastrointestinal bleeding. We recently treated two patients with this condition who presented with gastrointestinal bleeding and were diagnosed with gastrointestinal stromal tumours. We report the unique aspects of these cases and discuss the diagnostic and management problems that are posed by this unusual association.

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