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Review
. 2004 Jan;4(1):61-8.
doi: 10.2174/1389557043487510.

Rhenium-188 and copper-67 radiopharmaceuticals for the treatment of bladder cancer

Malcolm Frier  1
Affiliations
Review

Rhenium-188 and copper-67 radiopharmaceuticals for the treatment of bladder cancer

Malcolm Frier. Mini Rev Med Chem. 2004 Jan.

Abstract

The favourable nuclear properties of copper-67 and rhenium-188 for therapeutic application are described, together with methods for the chemical synthesis of a number of derivatives. Survival from invasive bladder cancer has changed little over the past 20 years. The intravesicular administration of Cu-67 or Re-188 radiopharmaceuticals in the treatment of bladder cancer offers some promise for improvement in this situation.

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